Table 1.
Clinical characteristics of sepsis patients involved (n = 68).
| Survival (n = 45) | Death (n = 23) | χ2/t/Z | p-value | |
|---|---|---|---|---|
| Infection site | ||||
| Respiratory system n (%) | 15 (33.3) | 8 (34.8) | 0.505 | 0.888 |
| Digestive system n (%) | 21 (46.7) | 12 (52.2) | ||
| Urogenital system n (%) | 9 (20) | 3 (13) | ||
| Physiological index | ||||
| Female n (%) | 20 (44.4) | 8 (34.8) | 0.587 | 0.603 |
| Age year | 64.5 ± 15.3 | 66.5 ± 12.8 | 0.542 | 0.590 |
| Temperature °C | 36.70 (36.5–37.9) | 36.50 (36.4–36.9) | 1.345 | 0.179 |
| HR beats per minute | 101.3 ± 24.4 | 106.8 ± 20.9 | 0.919 | 0.362 |
| RR breaths per minute | 24 (21.5–26.5) | 23 (22–27) | 0.052 | 0.958 |
| SBP mmhg | 105 (89.5–125) | 98 (92–126) | 0.266 | 0.790 |
| MAP mmhg | 80.3 ± 15.9 | 80.9 ± 13.4 | 0.140 | 0.889 |
| Laboratory results | ||||
| WBC × 109/L | 9.8 (7.2–16.1) | 12.5 (6∼23.4) | 0.369 | 0.712 |
| Neutrophil % | 85.9 (80.3–90) | 89.2 (82.2–93.5) | 1.783 | 0.075 |
| Lymphocyte % | 8 (4.5–13.2) | 5.4 (3.3–12.8) | 1.239 | 0.215 |
| Platelet × 109/L | 131 (70.5–186) | 72 (57–181) | 1.582 | 0.114 |
| PT s | 14 (12.9–15.8) | 13.9 (12.5–16.1) | 0.272 | 0.785 |
| APTT s | 35.8 (31.2–39.7) | 40.9 (31.4–44.8) | 1.439 | 0.150 |
| Total bilirubin umol/L | 26 (17.7–42.3) | 33.2 (24.4–79.2) | 1.290 | 0.197 |
| ALT U/L | 30 (19–57) | 34 (19–84) | 0.318 | 0.750 |
| AST U/L | 42 (27∼65.5) | 35 (27–68) | 0.078 | 0.938 |
| Creatinine umol/L | 78 (62–153) | 134 (76–255) | 1.491 | 0.136 |
| Cystatin C mg/L | 1.4 (1.3–2.1) | 1.8 (1.4–3) | 1.789 | 0.074 |
| Lactic acid mmol/L | 1.5 (1∼2.3) | 2.7 (1.3–6.3) | 2.530 | 0.011* |
| Disease score | ||||
| APACHE II | 13 (10–16) | 15 (11–17) | 0.833 | 0.405 |
| SOFA | 6 (5–8) | 9 (6–11) | 2.167 | 0.030* |
| quick SOFA | 2 (2–3) | 2 (2–3) | 0.815 | 0.415 |
| NEWS | 5.9 ± 3 | 7.6 ± 4 | 1.966 | 0.054 |
Abbreviations: HR, heart rate; RR, respiratory rate; SBP, systolic blood pressure; MAP, mean arterial pressure; WBC, white blood cell; PT, prothrombin time; APTT, activated partial prothrombin time; ALT, alanine aminotransferase; AST, aspartate aminotransferase; APACHE II, acute physiology and chronic health evaluation II; SOFA, sequential organ failure assessment; NEWS, national early warning score.