TABLE 1.
Patient clinicopathological characteristics and TS polymorphism variant analysis in 140 NSCLC patients harbouring driver EGFR mutations.
| Characteristics | TS polymorphism, n (%) | ||||
|---|---|---|---|---|---|
| Wild type | 3R | 3R + 6bp‐ | 6bp‐ | ||
| 68 (49) | 6 (4) | 25 (18) | 41 (29) | ||
| Sex, n (%) | Male | 27 (19) | 4 (3) | 5 (4) | 14 (10) |
| Female | 41 (29) | 2 (1) | 20 (14) | 27 (19) | |
| Age, years, n (%) | <65 | 46 (33) | 5 (4) | 18 (13) | 22 (16) |
| ≥65 | 21 (15) | 1 (1) | 7 (5) | 20 (14) | |
| Stage, n (%) | I | 18 (13) | 3 (2) | 6 (4) | 9 (6) |
| II | 5 (4) | 0 (0) | 1 (1) | 3 (2) | |
| III | 3 (2) | 11 (8) | 2 (1) | 5(4) | |
| IV | 39 (28) | 2 (1) | 15 (11) | 19 (14) | |
| NA | 2 (1) | 0 (0) | 1 (1) | 6 (4) | |
| EGFR mutation, n (%) | 19DEL | 25 (18) | 2 (1) | 11 (8) | 16 (11) |
| 21L858R | 33 (24) | 3 (2) | 11 (8) | 22 (16) | |
| 19DEL and 21L858R | 0 (0) | 0 (0) | 0 (0) | 1 (1) | |
| Rare mutations | 8 (6) | 1 (1) | 3 (2) | 4 (3) | |