Fig. 1.

Color fundoscopic images (right eye: A, left eye: B), autofluorescence (AF) images (right eye: C, left eye: D), and angiographic images (right eye: E, G; left eye: F, H) at the initial visit.

A) Yellowish placoids within a size of approximately 5 optic disc diameters are present in the macular area. The papilledema was unremarkable. B) Soft exudate was observed (blue arrow), presumably caused by diabetes. There were no placoid lesions or typical signs of acute syphilitic posterior placoid retinitis (ASPPC). C) AF imaging shows a hyperautofluorescent area corresponding to the placoid lesion. D, F, H) Small microvascular aneurysms are presumed to be the result of diabetes, and a hyperfluorescent area is observed in the upper nasal area of the fovea, but no typical signs of ASPPC are seen in the left eye. E) Fluorescein angiography (FA) shows excessive leakage in the placoid lesion and optic disc in the late phase before treatment, especially at the edge of the lesion. Hypofluorescent spots were observed in the inner area of placoid lesions. G) Indocyanine green angiography (ICGA). The hypofluorescent area corresponds to the hyperfluorescent area on FA, suggesting a blood flow deficit in the choroid. (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)