Fig. 7.

Electrospun fiber-based hernia meshes. A. Schematic illustration of the fabrication of a functional electrospun mesh by combining PCL with silk fibroin (SF) and decellularized human amniotic membrane (HAM) for full-thickness defect repair [331]. B. Schematic illustration of a functional “outer inner” medicated fibrous membrane preparation and the regulated early exogenous and long-term endogenous inflammation process in a rat abdominal wall hernia model. A traditional Chinese medicine was loaded onto the fiber by micro-sol electrospinning technique while a functional peptide was modified on the fiber surface [320]. C. An illustration of the design and fabrication process of a double-layer structured nanofiber membrane made by PCL, graphene oxide and chitosan with excellent mechanical strength and biocompatibility [319]. D. The electron scanning microscopic images of human vaginal fibroblast proliferation on the bFGF-modified PLLA fibers to promote hernia repair and the cell proliferation assay by cell count kit study [77].