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. 2023 Jun 29;21:100691. doi: 10.1016/j.mtbio.2023.100691

Table 6.

Hydrogel hernia scaffolds.

Classification Component Functions References
Natural Hydrogel Scaffolds Collagen Matrix deposition, angiogenesis, adipogenesis and skeletal muscle regeneration; Reduced postoperative adhesion, induced tissue re-mesothelialization [284,300,301]
Chitosan Quick cellular response, rapid ECM deposition, and improved neovascularization [302]
Gelatin Mild postoperative adhesion, sufficient neovascularization, induced collagen deposition and better collagen organization [303]
ECM Matrix Anti-inflammatory response; Elevated myogenic differentiation; Reduced scaffold encapsulation; Increased wall thickness and enhanced cellular infiltration [304,305,306]
Cellulose Effective prosthesis integration, induced tissue remodeling [307]
Fibrin Reduced hernia recurrence, increased fibrosis [308]
Synthetic Hydrogel Scaffolds HA derivatives Ameliorated postoperative peritoneal adhesion; Effective defect sealing [309,310]
GelMA Anti-inflammation; Rapid collagen deposition [311]
PVA Anti-Deformation, anti-adhesion, and pro-healing characteristics [312]
Resilin High strength and super-toughness, outstanding biocompatibility, and reduced tissue adhesion [313]