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. 2023 Jun 29;21:100691. doi: 10.1016/j.mtbio.2023.100691

Table 7.

Electrospun fibrous hernia meshes.

Classification Components Functions References
Simple electrospun hernia meshes PCL Sufficient biomechanical reinforcement; Enhanced suture retention and tensile strengths [329,330]
PLGA Well-matched mechanical strength, enhanced collagen deposition [73]
Composite electrospun hernia meshes PLCL ​+ ​fibrinogen Moderate mechanical strength; Excellent biocompatibility; Rapid muscle reconstruction [282,323,325]
PCL ​+ ​silk fibroin better cell proliferation microenvironment, increased angiogenesis, less-intensive adhesion formation [331]
PLA ​+ ​Collagen Enhanced cell adhesion and proliferation in vitro; Improved myogenesis and αSMA formation in vivo [332]
PCL ​+ ​Upy Good tissue compliance [326,328]
PCLMA ​+ ​GelMA Tunable mechanical properties, high biocompatibility, less inflammatory response, good biodegradation, and collagen deposition [321]
PEUU ​+ ​ECM gel Proper mechanical strength, extensive cellular infiltration, well tissue integrative behavior [322,306]
Carrier fiber meshes Antibacterial agent Controlled drug release; Inhibited bacterial growth; Reduced immune cell infiltration; Suppressed inflammatory reaction [327,333,334,335]
Antiinflammation agent Local inflammatory regulation; Improved collagen deposition and neovascularization; Attenuated visceral adhesion formation [318,320,77]
Cells Enhanced tissue regeneration, rapid vascularization; good biocompatibility and anti-inflammatory performance [260,336]
Multi-layer fibrous hernia meshes PCL ​+ ​graphene oxide ​+ ​chitosan excellent mechanical
strength and biocompatibility; excellent anti-hernia effects; less adhesion formation and more collagen deposition
[319]