Fig. 3.

Radiological features of VETC-positive HCCs.

(A) An axial arterial phase image of two HCCs on Gd-EOB-DTPA-enhanced MRI: one with peripheral irregular rim-like enhancement which has been associated with VETC positivity (white arrowhead) next to one with a more homogeneous enhancement associated with VETC negativity (white arrow). The patient subsequently received a liver transplant and explant pathology confirmed the respective VETC statuses associated with these two HCCs. (B) An axial arterial and (C) portal venous phase image of an 8 cm HCC on a contrast-enhanced CT scan with radiological features associated with the VETC pattern: size >5 cm, intratumoural necrosis (asterisk) and well-defined capsule (white arrowheads). The HCC was subsequently resected with histology demonstrating a VETC-positive HCC.