Table 1.
Comparation of clinical parameters and neurophysiological test results between Control and DPN group
| Control group (n = 55) | DPN group (n = 65) | P | |
|---|---|---|---|
| Age (years) | 58 (51–64) | 57 (51.5–67) | 0.666b |
| Female (n, %) | 20, 36.36 | 24, 36.92 | 0.949c |
| High (cm) | 169 (160–172) | 167 (160.5-173.5) | 0.870 |
| Weight (kg) | 70 (60-77.5) | 69 (60.25–81.5) | 0.802 |
| BMI (kg /m2) | 24.62 (22.66–26.54) | 24.88 (21.91–27.84) | 0.796b |
| Duration of DM (years) | 8 (3–12) | 10 (1-18.5) | 0.346b |
| Duration of Hypertension (years) | 0.00 (0.00–10.00) | 0.00 (0.00-9.50) | 0.963b |
| FPG (mmol/l) | 8.92 ± 3.08 | 10.21 ± 4.02 | 0.054a |
| FCP (nmol/l) | 0.40 (0.24–0.55) | 0.27 (0.17–0.47) | 0.058b |
| HOMA-IR | 2.62 (2.17–3.35) | 2.41 (2.12–3.27) | 0.464b |
| HbA1c (%) | 9.0 (7.3–10) | 10.3 (8.85–12.2) | 0.001b* |
| TG (mmol/l) | 1.77 (1.25–2.45) | 1.67 (1.10–2.54) | 0.431b |
| TC (mmol/l) | 4.51 (3.7–5.02) | 4.62 (4.01–5.35) | 0.111b |
| HDL-C (mmol/l) | 0.85 (0.68–1.06) | 0.87 (0.69–1.13) | 0.484b |
| LDL-C (mmol/l) | 2.34 ± 0.87 | 2.68 ± 0.98 | 0.052a |
| Statin (n, %) | 25, 45.45 | 32, 49.23 | 0.680c |
| Other lipid-lowering drugs (n, %) | 4, 7.27 | 6, 9.23 | 0.699c |
| Motor conduction | |||
| Ulnar nerve (m/s) | 61.20 (59–63) | 54.40 (51.35–59.80) | 0.000b* |
| Radial nerve (m/s) | 64.60 (62.55–66.20) | 62.50 (60.85–64.62) | 0.001b* |
| Median nerve (m/s) | 60.00 (55.65–62.15) | 53.50 (49.75–56.03) | 0.000b* |
| Tibial nerve (m/s) | 47.28 ± 3.17 | 41.00 ± 3.63 | 0.000a* |
| Common peroneal nerve (m/s) | 46.75 (44.85–48.50) | 42.15 (38.88–44.55) | 0.000b* |
| Sensory conduction | |||
| Ulnar nerve (m/s) | 55.94 ± 4.79 | 48.72 ± 5.90 | 0.000a* |
| Radial nerve (m/s) | 57.17 ± 8.27 | 50.71 ± 6.67 | 0.000a* |
| Median nerve (m/s) | 56.83 ± 5.61 | 45.47 ± 7.60 | 0.000a* |
| Sural nerve (m/s) | 52.05 ± 4.96 | 44.68 ± 5.39 | 0.000a* |
The data are presented as n (%), or the median (inter-quartile range) unless otherwise specified
a Student’s t test was employed for normally distributed variables
b The Mann-Whitney U test was employed for asymmetrically distributed variables
c The Chi-square test was employed for categorical variables
*P < 0.05
Abbreviations: DPN, diabetic peripheral neuropathy; BMI, body mass index; DM, diabetes mellitus; FPG, fasting plasma glucose; HbA1c, glycosylated hemoglobin; FCP, fasting C-peptide; TG, triglycerides; TC, total cholesterol; LDL-C, low density lipoprotein cholesterol; HDL-C, high density lipoprotein cholesterol