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. 2023 Jul 12;21:464. doi: 10.1186/s12967-023-04268-3

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© The Author(s) 2023

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Fig. 1 — CHCHD4 is identified as a regulator of PAH. A Differential expression CHCHD protein among CHCHD protein family in PAH patients (GSE113439). B Quantitative real time PCR (qPCR) analysis of Chchd4 transcription in lung tissues from indicated animals (n = 4). C Representative immunoblotting of CHCHD4 in lung tissues (n = 6), Normalized to β-Actin. D Representative HE staining verified successful PAH model. E Representative immunofluorescence of α-SMA (green), CHCHD4 (red) and DAPI (blue) in lung tissues from indicated group. Data are shown as the mean ± SEM. P value is showed in each figure