Table 1.
Demographics and clinical variables of patients (before PSM).
| Variables | Case group (n = 50) | Control group (n = 924) | Statistics | P-value |
|---|---|---|---|---|
| Age of onset | 36 (30.0, 49.3) | 48 (37, 56) | −3.28 | 0.001* |
| Males: Females | 37:13 | 465:459 | 10.65 | 0.001* |
| Side (Left: Right) | 24:26 | 475:449 | 0.22 | 0.64 |
| Time to treatment (days) | 10 (4, 20) | 7 (3, 13) | −2.63 | 0.009 * |
| Hypertension | 5 (10%) | 176 (19%) | 2.57 | 0.11 |
| Diabetes mellitus | 1 (2%) | 120 (12.9%) | 5.26 | 0.02* |
| Initial PTA (dB) | 58.9 ± 3.4 | 81.3 (56.3, 100) | −4.65 | 0.00* |
| Final PTA (dB) | 48.3 ± 3.7 | 52.5 (30, 75) | −1.29 | 0.19 |
| Hearing gain (dB) | 6.25 (1.3, 19.1) | 20 (6.3, 38.8) | −4.48 | 0.00* |
| Tinnitus | 45 (90%) | 857 (92.7%) | 0.52 | 0.41 |
| Vertigo | 16 (32%) | 513 (55.5%) | 10.57 | 0.001* |
| Aural fulness | 39 (78%) | 595 (64.4%) | 3.86 | 0.04* |
| Vestibular dysfunction | 35 (70%) | 768 (83.1%) | 5.64 | 0.02* |
| Inner ear MRI (+) | 12 (24%) | 482 (52.2%) | 15.1 | 0.00* |
| Thyroid dysfunction | 8 (16%) | 241 (26.1%) | 2.53 | 0.11 |
| Effective cases | 15 (30%) | 542 (58.7%) | 15.9 | 0.00* |
| Blood index | ||||
| NLR | 1.7 (1.4, 2.5) | 1.8 (1.4, 2.5) | −0.38 | 0.70 |
| MLR | 0.19 (0.15, 0.29) | 0.19 (0.14, 0.24) | −1.51 | 0.13 |
| PLR | 114.3 (87.9, 135.4) | 115.4 (91.4, 148.4) | −0.44 | 0.66 |
| TBIL (μmol/L) | 13.1 (10.7, 16.5) | 13.4 (10.5, 17.3) | −0.06 | 0.95 |
| IBIL (μmol/L) | 9.4 (7.5, 11.3) | 9.8 (7.4, 12.8) | −0.46 | 0.64 |
| SOD (U/mL) | 158.5 (144.0, 189.5) | 164 (139.3, 192) | −0.04 | 0.97 |
| Fibrinogen (g/L) | 2.3 (2.1, 2.7) | 2.4 (2.1, 2.8) | −0.42 | 0.68 |
| Glu (mmol/L) | 4.9 (4.6, 5.2) | 5.0 (4.6, 5.7) | −1.98 | 0.04 * |
| TG (mmol/L) | 1.4 (0.9, 1.8) | 1.4 (0.9, 2.1) | −1.16 | 0.25 |
| CH (mmol/L) | 4.8 ± 0.1 | 4.9 (4.2, 5.7) | −0.84 | 0.39 |
| HDL (mmol/L) | 1.3 (1.0, 1.5) | 1.3 (1.1,1.5) | −0.48 | 0.64 |
| LDL (mmol/L) | 2.9 ± 0.1 | 2.9 (2.3, 3.5) | −0.38 | 0.70 |
| Hcy (μmol/L) | 10.7 (7.9, 14.9) | 9.4 (7.4, 12.2) | −2.27 | 0.02 * |
PTA, pure-tone average; NLR, neutrophil lymphocyte ratio; MLR, monocyte lymphocyte ratio; PLR, platelet lymphocyte ratio; TBIL, Total bilirubin levels; IBIL, indirect bilirubin; SOD, superoxide dismutase; Glu, glucose; TG, triglyceride; CH, cholesterol; HDL, high-density lipoprotein; LDL, low-density lipoprotein; Hcy, homocysteine.
*P < 0.05.