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. 2023 Jul 12;12(2):2225638. doi: 10.1080/22221751.2023.2225638

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© 2023 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group, on behalf of Shanghai Shangyixun Cultural Communication Co., Ltd

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The terms on which this article has been published allow the posting of the Accepted Manuscript in a repository by the author(s) or with their consent.

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Figure 1. — The neutralization capacities of convalescent sera from BA.5/BF.7 breakthrough infections against the pseudotyped viruse BF.7 (A) compared to BA.5, against the pseudotyped viruse D614G (B), Delta (C), BA.1 (D), BQ.1.1 (E), XBB.1.5 (F) and CH.1.1 (G) compared to BA.5/BF.7, The neutralization activity of 63 convalescent sera from COVID-19 patients was tested. The neutralization ID50 and decreased fold compared to the reference strain BA.5 or BA.5/BF.7 was also displayed as indicated. Data represented ID50 of three independent experiments. H. The heatmap of individual neutralization data. Data represented mean ID50 of three independent experiments. The red to yellow colour represented ID50 high to low as shown in the scale bar. S1–S63 sera were collected 1-month after recovery. The effects of gender (I), age (J), and the interval between the last vaccination and breakthrough infection (K) on the immune responses. n in the figure represents the number of samples.