Figure 3.

Interaction of EVs with monolayer MoS₂ embedded in MoSERS microchip. (a) The SEM image of the EVs immobilized on a triangular single crystalline monolayer MoS₂ demonstrating the attraction of the nanocavity array. (b) High-resolution SEM image of the EVs. (c) High-resolution TEM image of coexisting monolayer MoS₂ and EV. (d) Representative simulated trajectory of the restrictive simulation (e) The atom contacts number and the center of mass (COM) distance between the MoS₂ nanosheet and the lipid membrane. (f) Representative trajectories of the released simulation. Angle between the lipid bilayer and the MoS₂ basal. (g) The interaction energy between the MoS₂ nanosheet and the EV’s bilayer lipid. (h) Normalized contact number of each component of the phospholipid bilayer.