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. 2023 Jun 26;13(13):2167. doi: 10.3390/diagnostics13132167

Table 5.

sNfL and sGFAP in Long-COVID patients with neurological associated symptoms such as headache (sNfL n = 16, sGFAP n = 15), fatigue (sNfL n = 21, sGFAP n = 14), anosmia (sNfL n = 19, sGFAP n = 18) and ageusia (sNfL n = 19, sGFAP n = 19) prior to a SARS-CoV2 infection and during the Long-COVID period. The Wilcoxon test was used to assess group differences.

sNfL before Infection vs. after Infection sGFAP before Infection vs. after Infection
Symptoms Median IQR p-Value Median IQR p-Value
headache 6.9 to 6.9 5.8 to 8.4 vs.
5.5 to 7.8
p = 0.29 67.7 to 66.9 52.0 to 79.5 vs.
45.2 to 73.5
p = 0.71
fatigue 7.3 vs. 6.9 5.8 to 9.3 vs.
5.5 to 8.4
p = 0.17 66.8 to 69.9 47.4 to 82.7 vs.
51.8 to 86.0
p = 0.39
anosmia 7.3 vs. 6.7 5.3 to 8.8 vs.
50.6 to 8.3
p = 0.35 59.0 vs. 60.9 47.9 to 74.6 vs.
50.1 to 70.1
p = 0.35
ageusia 6.7 vs. 6.6 5.3 to 8.6 vs.
5.6 to 7.9
p = 0.23 61.7 vs. 60.7 49.5 to 76.8 vs.
45.3 to 71.0
p = 0.16