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Overview of the mAbs and engineered engagers targeting B7-H3. NK, natural Killer cells; T, T cells; M, macrophages; TAA, tumor-associated antigen; FcR, Fc receptor; BITE, bi-specific T-cell engager; TriKE, tri-specific killer engager; NKCE, natural killer cell engager; IL-2R, IL-15R, and TGFbetaR, receptors for IL-2, IL-15, and TGFbeta cytokines, respectively (Created by BioRender.com (URL accessed on 16 June 2023)).
