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(a) A 50-year-old patient with extensive HER2-positive breast cancer in right upper outer quadrant. (b) MRI showed extensive mass and non-mass-like enhancement spanning 10 cm. The patient received neoadjuvant weekly Paclitaxel and Herceptin with Pertuzumab for three months. (c) post-NAST MRI showed a complete radiological response. The patient underwent nipple-sparing mastectomy and reconstruction with SLNB. The final histology confirmed pCR.
