Table 1.
Studies included in the systematic review and pooled analysis. pCR: complete pathological response to neoadjuvant therapy; ypN+: pathologically node-positive disease after neoadjuvant systemic therapy (NAST).
| Study | Citation | Study Design | Number of Patients (N) | ypN+ Cases (%) | Comments |
|---|---|---|---|---|---|
| Tadros A.B et al. | [8] | Prospective cohort | 116 | 0 (0) | pCR |
| Barron et al. | [9] | Retrospective | 3240 | 75 (0.03) | pCR |
| Zhi-Qiang et al. | [10] | Retrospective | 17 | 0 (0) | pCR |
| Samiei et al. | [11] | Retrospective registry | 353 | 4 (1.1) | pCR |
| Weiss et al. | [12] | Retrospective | 108 | 4 (3.7) | pCR |
| Total | 3834 | 83 (2.16) | Overall ypN+ = 2.16% |