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Mechanism of action of anti-VEGF agents in colorectal cancer. Abbreviations: placenta-derived growth factor (PIGF), vascular endothelial growth factor (VEGF), vascular endothelial growth factor receptor (VEGFR), multi-kinase inhibitor (MKI), and mAb (monoclonal antibody). This figure was reprinted with permission from an open access journal [38].
