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Exons in the osteopontin gene. (A) OPN (SPP1) exons on chromosome 4. (B) The exons that are translated from the OPN mRNAs into the extracellular forms, OPN-a, OPN-b, OPN-c, and OPN-4, and the intracellular form, OPN-5, with its unique exon (in green). The full-length protein of 314 amino acids, OPN-a, is translated from the upper splice variant. Thrombin cleavage site: red arrow. ATG: start codon. TAA: stop codon. Created with BioRender.com.
