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. 2023 Jul 7;12(13):1804. doi: 10.3390/cells12131804

Table 5.

Functional pathways uniquely dysregulated by 50 µM APAP + GEN mixture in PND8 rat Sertoli cells.

PND8 Rat Sertoli Cells
Pathway Description Enrichment Score p-Value Genes
Foxo signaling pathway 8.6 0.000180 7
Melanoma 3.7 0.0252 3
Glioma 3.6 0.0283 3
PI3K-Akt signaling pathway 3.5 0.0298 7
Pancreatic cancer 3.5 0.0316 3
Rheumatoid arthritis 3.5 0.0316 3
Hematopoietic cell lineage 3.4 0.0351 3
JAK-STAT signaling pathway 3.3 0.0368 4