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. 2023 Jul 2;15(13):3469. doi: 10.3390/cancers15133469

Table 2.

Assessment of the type of treatment and selected parameters.

Characteristic Number of Cases (n) First-Line Treatment Used (%) Independence Assessment
p Value
Correlation Assessment
φc or rφ *
Three-Drug Treatment Two-Drug Treatment
Sex
Male 100 80 (80.0%) 20 (20.0%) 0.999 -
Female 97 77 (79.4%) 20 (20.6%)
ISS φc
ISS I 25 21 (84.0%) 4 (16.0%) 0.602 0.081
ISS II 66 55 (83.3%) 11 (16.7%)
ISS III 96 74 (77.0%) 22 (23.0%)
Presence of bone changes
Yes 154 125 (81.2%) 29 (18.8%) 0.644 -
No 36 28 (77.8%) 8 (22.2%)
Calcium level above 2.75 mmol/L
Yes 28 25 (89.3%) 3 (10.7%) 0.305 -
No 168 132 (78.6%) 36 (21.4%)
Creatinine above 1.9 mg/dL
Yes 44 28 (63.6%) 16 (36.4%) 0.005 -
No 153 129 (84.3%) 24 (15.7%)
ECOG φc
ECOG 0 16 14 (87.5%) 2 (12.5%) 0.866
ECOG 1 84 68 (81.0%) 16 (19.0%)
ECOG 2 71 54 (76.1%) 17 (23.9%) 0.090
ECOG 3 18 14 (77.8%) 4 (22.2%)
ECOG 4 8 7 (87.5%) 1 (12.5%)
Physical fitness, according to Katz φc
Fully independent 158 130 (82.3%) 28 (17.7%) 0.162 0.139
Moderate impairment 23 15 (65.2%) 8 (34.8%)
Completely dependent 11 9 (81.8%) 2 (18.2%)
Frailty score (IMWG)
Intermediately fit 43 34 (85.0%) 9 (15.0%) 1.000 −0.010
Frailty 154 123 (79.8%) 31 (20.8%)

Abbreviations: ECOG—Eastern Cooperative Oncology Group; ISS—International Staging System. * Cramer’s V correlation (φc); Phi correlation (rφ); IMWG—International Myeloma Working Group.