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Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
Obefazimod binds to and stabilizes cap-binding complex (CBC), leading to enhanced splicing of the miR-124 precursor, and thus, increased production of miR-124. This results in less pro-inflammatory signaling (e.g., via IL-6 and STAT3). Created with biorender.com.