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. 2023 Jun 27;12(13):1730. doi: 10.3390/cells12131730

Figure 3.

Figure 3

Obefazimod binds to and stabilizes cap-binding complex (CBC), leading to enhanced splicing of the miR-124 precursor, and thus, increased production of miR-124. This results in less pro-inflammatory signaling (e.g., via IL-6 and STAT3). Created with biorender.com.