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. 2023 Jun 27;15(13):3369. doi: 10.3390/cancers15133369

Table 1.

Summary of relevant literature on glioma grading and the corresponding methodologies used. For each study, we report details about the database used, sample size, MRI modality, data spitting strategy, dimensionality, number of slices used, categories considered, and the reported performance.

Reference Database Sample Size MRI Modality Split Dimensionality Slices Classes Performance
Yang et al. [9] Private 113 T1ce Patient 2D ≥80% tumor LGG/HGG OA = 0.945
AUC = 0.968
Pereira et al. [10] BraTS2017 285 T1, T1ce, T2, FLAIR Patient-level 3D All LGG/HGG OA = 0.9298
AUC = 0.9841
Recall LGG = 0.867
Recall HGG = 0.952
Banerjee et al. [11] BraTS2017 746 T1, T1ce, T2, FLAIR Patient 2D largest slice ± 10 LGG/HGG OA = 0.970
TCGA Recall LGG = 0.96
Recall HGG = 0.943
Anaraki et al. [12] IXI 1288 T1ce Slice 2D tumor visible Normal/G.2/G.3/G.4 OA = 0.909
REMBRANDT Recall Normal = 0.998
TCGA Recall G.2 = 0.884
private Recall G.3 = 0.864
Recall G.4 = 0.974
Tandel et al. [13] REMBRANDT 130 T2 Slice 2D tumor visible Normal/LGG/HGG OA = 0.960
AUC = 0.990
Zhuge et al. [14] Brats2018 315 T1ce, T2, FLAIR Patient 2D largest slice LGG/HGG OA = 0.963
TCGA Recall HGG = 0.935
Recall LGG = 0.972
Patient 3D All LGG/HGG OA = 0.971
Recall HGG = 0.947
Recall LGG = 0.968
Ayadi et al. [16] REMBRANDT 130 Slice 2D tumor visible Normal/LGG/HGG OA = 0.972
Recall Normal = 1
Recall LGG = 0.984
Recall HGG = 0.860
Radiopaedia 121 Slice 2D tumor visible G.1/G.2/G.3/G.4 OA = 0.937
Recall G.1 = 0.901
Recall G.2 = 0.957
Recall G.3 = 0.908
Recall G.4 = 0.982
Ding et al. [17] Private 151 T1ce Patient 2D largest + 2 adjacent LGG/HGG OA= 0.800
TCGA AUC = 0.898
Recall LGG = 0.760
Recall HGG = 0.840
van der Voort et al. [18] EGD 1748 T1, T1ce, T2, FLAIR Patient 3D All LGG/HGG OA = 0.84
REMBRANDT AUC = 0.91
CPTAC-GBM Recall LGG = 0.72
TCGA Recall HGG = 0.93
BraTS2019 G.2/G.3/G.4 OA = 0.71
Ivy GAP AUC = 0.81
Private Recall G.2 = 0.75
Recall G.3 = 0.17
Recall G.4 = 0.95

OA = Overall Accuracy, AUC = Area Under the (ROC) Curve.