Table 3.
Clinical and laboratory features shared between KD and HIES.
| Clinical and Laboratory Features | KD | HIES |
|---|---|---|
| Raised serum IgE and eosinophilia | ✓ | ✓ |
| Fever, rash, and mucocutaneous involvement | ✓ | ✓ |
| Susceptibility to Staphylococcus aureus and Candida albicans | ✓ | ✓ |
| Lymphadenopathy | ✓ | ✓ |
| Vasculitis, CAAs, MI | ✓ | ✓ |
| Response to IVIG with resolution of symptoms | ✓ | ✓ |
| Expansion of CD4+ effector memory T cells | ✓ | ✓ |
Abbreviations: CAAs: Coronary artery abnormalities; HIES: Hyper IgE syndrome; IgE: Immunoglobulin E; IVIG: Intravenous immunoglobulin; KD: Kawasaki disease; MI: Myocardial infarction.