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. 2023 Jun 30;13(13):2229. doi: 10.3390/diagnostics13132229

Table 2.

Univariate and multivariate Cox proportional hazards analysis for AE a.

Variable HR h Univariate Analysis B p Value Multivariate Analysis
95% CI i HR h 95% CI i p Value
Lower Level Upper Level Lower Level Upper Level
Male gender 2.600 1.676 4.032 0.955 <0.001 2.525 1.441 4.425 0.001
Age (years) 1.045 1.021 1.070 0.044 <0.001 1.042 1.017 1.067 0.001
Hypertension 1.542 0.935 2.543 0.433 0.089
Hyperlipoproteinemia 1.086 0.698 1.634 0.066 0.762
Smoking 1.395 0.910 2.139 0.333 0.126
Diabetes 2.523 1.576 4.038 0.925 <0.001 1.891 1.171 3.055 0.009
Family history of CAD b 0.894 0.585 1.365 −0.113 0.603
Typical chest pain 2.495 1.449 4.296 0.914 0.001 0.838 0.420 1.670 0.615
SECHO c/SECG d 0.989 0.641 1.525 −0.011 0.959
Duration of the test (minutes) 0.945 0.875 1.021 −0.056 0.151
Achieved target heart rate 0.682 0.429 1.086 −0.382 0.107
Maximum achieved SBP e 1.007 0.997 1.017 0.007 0.157
Maximum achieved DBP f 1.000 0.982 1.019 0.000 0.976
Chronotropic index < 0.8 1.765 1.144 2.724 −0.568 0.010 1.493 0.955 2.332 0.079
Slow HRR g 3.084 1.638 5.808 1.126 <0.001 2.024 1.041 3.939 0.038

a AEs—adverse events (death + myocardial infarction + CABG + PCI), b CAD—coronary artery disease, c SECHO—stress echocardiography, d SECG—stress electrocardiography, e SBP—systolic blood pressure, f DBP—diastolic blood pressure, g HRR—heart rate recovery, h HR—hazard ratio, i CI—confidence interval.