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. 2023 Jul 4;20(13):6289. doi: 10.3390/ijerph20136289

Table 3.

Adjusted Odds Ratios of Prenatal Mental Health Conditions by Adverse Childhood Experiences (ACEs) Count and Individual ACE (N = 1084).

Anxiety Disorder Depressive Disorder Depression Symptoms IPV Diagnosis
aOR (95% CI) p aOR (95% CI) p aOR (95% CI) p aOR (95% CI) p
ACE count
1–2 vs. 0 ACEs 1.56 (1.01–2.42) 0.045 1.83 (1.28–2.61) <0.001 * 1.73 (1.08–2.77) 0.02 * 2.48 (1.46–4.22) <0.001 *
≥3 vs. 0 ACEs 2.90 (1.81–4.66) <0.001 * 2.83 (1.88–4.27) <0.001 * 3.00 (1.78–5.03) <0.001 * 4.40 (2.52–7.67) <0.001 *
Individual ACEs
Loss of parent 1.33 (0.88–2.00) 0.18 1.69 (1.20–2.37) 0.003 1.71 (1.11–2.63) 0.02 2.01 (1.27–3.17) 0.003
Emotional abuse 2.31 (1.50–3.56) <0.001 2.01 (1.38–2.92) <0.001 3.06 (1.94–4.81) <0.001 2.61 (1.60–4.25) <0.001
Physical abuse 1.79 (0.93–3.43) 0.08 1.95 (1.12–3.39) 0.02 1.46 (0.69–3.08) 0.33 2.13 (1.05–4.34) 0.04
Sexual abuse 1.91 (1.05–3.48) 0.03 2.38 (1.44–3.95) <0.001 1.62 (0.85–3.08) 0.14 3.08 (1.68–5.67) <0.001
Lived with someone:
-With substance use problem 2.07 (1.34–3.21) 0.001 2.03 (1.39–2.96) <0.001 1.60 (0.96–2.64) 0.07 2.83 (1.73–4.63) <0.001
-Who was depressed, mentally ill, or suicidal 2.32 (1.50–3.61) <0.001 2.38 (1.62–3.48) <0.001 3.36 (2.09–5.40) <0.001 2.76 (1.67–4.57) <0.001
-Who went to jail or prison 1.97 (1.11–3.49) 0.02 1.84 (1.11–3.03) 0.02 1.17 (0.60–2.27) 0.65 1.50 (0.77–2.93) 0.24
-Who hit, punched, beat, or threatened to harm another adult in the home 1.41 (0.77–2.55) 0.26 1.46 (0.88–2.41) 0.14 1.84 (1.00–3.39) 0.49 3.04 (1.69–5.46) <0.001

Notes. aOR = Adjusted odds ratio. ACE = Adverse childhood experience. IPV = Intimate partner violence diagnosis. All models were adjusted for age, race/ethnicity, median neighborhood household income, and parity. * indicates statistical significance after applying the Benjamini-Hochberg adjustment for false discovery rates.