Figure 3.
RPE nuclei identified by High-Res OCT. (A) OCT b-scan acquired with High-Res OCT showing the foveal area: Hyporeflective dots at the level of RPE correspond with RPE nuclei (arrows). Mononucleated RPE cell (black arrows), probably binucleated RPE cell (white arrow). The ELM, ellipsoid zone (EZ), interdigitation zone (IZ), RPE–BM complex, choriocapillaris (CC), and Sattler's layer are listed for guidance. (B) OCT b-scan acquired with spectral domain OCT (Spectralis HRA-OCT) representing the same area. Scale bars, 50 µm. (C) Hematoxylin and eosin–stained perifoveal histological section of a human donor retina with basophilic RPE nuclei (magenta; arrows) and underlying BM. Melanosomes and/or phagolysosomes show brown pigmentation and apical microvilli appear transparent. Original magnification ×40.