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. 2023 Jul 5;12(13):1783. doi: 10.3390/cells12131783

Table 2.

Brentuximab vedotin’s function in various lymphomas.

Brentuximab Vedotin’s Function in Various Lymphomas
Classical Hodgkin lymphoma
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    Option for patients with recurrent classical Hodgkin lymphoma that did not respond to high-dose chemotherapy and autologous stem cell transplantation (HDCT/ASCT) or two prior chemotherapy regimens regardless of eligibility for HDCT/ASCT;

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    intravenous brentuximab vedotin = in consolidation therapy after ASCT and salvage therapy for CD30-positive HL.
ALCL
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    approved for the treatment of systemic ALCL in adult patients who have not responded to prior multi-agent chemotherapy or who are not candidates for ASCT;

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    is not typically used as a first-line treatment for primary cutaneous ALCL.
Mycosis Fungoides
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    brentuximab vedotin may be utilized in the treatment of MF with CD30 expression when it is refractory to other treatments or in cases of relapsed disease.