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. 2023 Jun 22;24(13):10484. doi: 10.3390/ijms241310484

Figure 2.

Figure 2

Effects of each of the 5 capsules composing the sequential MIM assessed after 3 days of treatment in hGF cells inflamed with IL-1β. (A) Cytotoxicity. Results are shown relative to LDH activity in cell culture media. Negative control = 0% cell death, positive control = 100% cell death (1% nonionic surfactant). (B) PGE2, (C) MMP-1, and (D) TIMP-1 protein released to cell culture media. Data represent media ± SEM of six sample replicates (n = 6) for each group. A and B were compared using ANOVA and LSD as post hoc, while C and D were compared using the Kruskal–Wallis test. +: Cells treated with IL-1β, -: Cells not treated with IL-1β. Statistically significant differences were considered for p < 0.05 and are represented with * compared to control and + compared to vehicle/inflammatory control.