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. 2023 Jun 30;24(13):10934. doi: 10.3390/ijms241310934

Figure 6.

Figure 6

HCQ effect on IL-8 and VCAM-1 in EO-PE fpECAs. When EO-PE fpECAs were incubated with increasing dosages of HCQ, there was no difference either on mRNA grade of VCAM-1 (A.I) or IL-8 (B.I) as well as on the membrane presence (A.II) of VCAM-1 between CTR and HCQ-treated EO-PE fpECAs. In contrast, a higher dosage of HCQ (10 µg/mL) downregulated the secretion of IL-8 in EO-fpECAs (B.II). RM one-way ANOVA with Sidak’s post hoc was used for statistical analysis. N = 7; * p ≤ 0.05; ns, not significant.