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Cytokine production in response to SPEA-based peptides in a mixed culture of PBMCs and MDA-MB-468 cells. (A) concentration of IL-6, (B) concentration of IL-10, (C) concentration of TNFα, and (D) concentration of IL-1β. Data presented as a mean concentration in pg/mL ± standard error of the mean (S.E.M) of 3 experiments (n = 3).* p ˂ 0.05, ** p ˂ 0.01, *** p ˂ 0.001, compared to treatment with the corresponding solvent (H2O for SP2, SP3, and PBS for SPEA).
