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. 2023 Jun 28;24(13):10787. doi: 10.3390/ijms241310787

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© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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All 16 MS patients with a Z-score above the threshold of 1.5 (indicated by the blue dashed line). In comparison, all but 5/16 for ELISA and 8/16 for Simoa, had a concentration above the threshold that has been set as 3 S.D. above the mean of the HC (indicated by the green and red dashed line). MS: Multiple Sclerosis; HC: Healthy Controls.