HD	Huntington’s disease
polyQ	polyglutamine
mHTT	Mutant Huntingtin protein
CREB	cAMP response element-binding protein
CBP	CREB binding protein
TBP	TATA-binding protein
SP1	specificity protein 1
TFs	transcription factors
GRN	Gene Regulatory Network
MRs	Master Regulators
WT	Wild-Type
DE	differentially expressed
GO	gene ontology
ChIP	Chromatin Immunoprecipitation
MSN	medium spiny neuron