Figure 3.

Comparison of quantified ZED1227-TG2 fluorescence intensities in the villous epithelium and lamina propria in the patient groups who received placebo, 10 mg, 50 mg, or 100 mg of ZED1227. The last oral drug dose was given 24 h before endoscopy and biopsy sampling (panel (A)). Panels (B,C) illustrate the regions drawn to define the epithelial and lamina propria measurement areas. Shown are the average fluorescence intensity ratios (pre- vs. post-treatment biopsies of each patient stained on the same slide). Original magnification in panels B and C, ×100.