Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
The Raf/MEK/ERK and PI3K/AKT/mTOR pathways and potential therapeutics. Different inhibitors target different mutations. They inhibit further signal transduction, ultimately preventing cell proliferation and survival or leading to apoptosis. Abbreviations: epidermal growth factor (EGF), epidermal growth factor receptor (EGFR).
