3-PEHPC |
2-hydroxy-2-phosphono-3-(pyridin-3-yl) propanoic acid |
AKT |
serine/threonine protein kinase B |
AMP |
adenosine monophosphate |
AP-1 |
activator protein 1 |
AP-3 |
adaptor protein 3 |
APC |
antigen presenting cell |
Bcl6 |
B cell lymphoma 6 |
CaM |
calmodulin |
CaMKIV |
calcium/calmodulin-dependent protein kinase IV |
CCR6 |
C-C-motif chemokine receptor 6 |
CD |
cluster of differentiation |
CD40L |
CD40 ligand |
cGVHD |
chronic graft versus host disease |
CIE |
clathrin-independent endocytosis |
CME |
clathrin-mediated endocytosis |
CpG |
cytosine and guanine separated by a phosphate |
CRE |
cyclic AMP responsive element |
CREB |
cyclic AMP responsive element-binding protein |
CREM |
cyclic AMP element modulator |
CXCL |
chemokine (C-X-C motif) ligand |
DN T |
double negative T cell |
Drp1 |
dynamin-related protein 1 |
EAE |
experimental autoimmune encephalomyelitis |
EEA1 |
early endosomal antigen 1 |
EGR2 |
early growth response 2 |
ELAVL1 |
embryonic lethal vision like protein 1 |
ERC |
endosomal recycling compartment |
FcεRIγ |
Fc epsilon receptor I gamma chain |
FoxP3 |
forkhead box P3 |
GAP |
GTPase-activating protein |
G-CSF |
granulocyte colony stimulating factor |
GDP |
guanosine diphosphate |
GEF |
guanine nucleotide exchange factor |
Gfi1 |
growth factor independent 1 transcriptional repressor |
GM-CSF |
granulocyte monocyte-colony stimulating factor |
GTP |
guanosine triphosphate |
GTPase |
guanosine triphosphatase |
HIF-1α |
hypoxia-inducible factor 1α |
HRES-1 |
HTLV-1 related endogenous retroviral sequence 1 |
ICER |
inducible cyclic AMP early repressor |
IFN |
interferon |
IFNAR1 |
Type I IFN receptor |
IL |
interleukin |
IL-6R |
interleukin 6 receptor |
IS |
immunological synapse |
ITAM |
immunoreceptor tyrosine-based activation motif |
JAK |
Janus kinase |
LAT |
linker for activation of T cells |
Lck |
lymphocyte-specific proteins tyrosine kinase |
MHC |
major histocompatibility complex |
miRNA |
microRNA |
mRNA |
messenger RNA |
MRL-lpr |
Murphy Roths Large-lymphoproliferation |
mTOR |
mechanistic target of rapamycin |
mTORC |
mechanistic target of rapamycin complex |
NFAT |
nuclear factor of activated T cells |
NF-κB |
nuclear factor-κB |
OXPHOS |
oxidative phosphorylation |
Pam3CSK4
|
Pam3-Cys-Ser-Lys4 |
PDK1 |
phosphatidylinositol-dependent kinase 1 |
PI3K |
phosphoinositol-3 kinase |
PI3P |
phosphoinositol-3-phosphate |
PIP2 |
phosphatidylinositol-4,5-biphosphate |
PIP3 |
phosphatidylinositol-3,4,5-triphosphate |
PKB |
serine/threonine protein kinase B |
PKC |
protein kinase C |
PLC-γ |
phospholipase Cγ |
PP2A |
protein phosphatase 2 |
RORγt |
retinoic-acid-receptor-related orphan nuclear receptor γ |
S6K |
ribosomal S6 kinase |
SH2 |
SRC homology domain 2 |
sIL-6R |
soluble IL-6 receptor |
SLE |
systemic lupus erythematosus |
SLP-76 |
SH2-domain-containing leukocyte protein of 76 kDa |
SMAC |
supramolecular activation complex |
SNPs |
single nucleotide polymorphisms |
SNX27 |
sorting nexin 27 |
SP-1 |
specificity protein 1 |
STAT |
signal transducer and activator of transcription |
Syk |
spleen tyrosine kinase |
TCR |
T cell receptor |
Tfh |
follicular helper T cell |
TGFβ |
transforming growth factor β |
TGN |
trans-Golgi network |
Th17 |
helper T 17 cell |
TLR |
toll-like receptor |
Treg |
regulatory T cell |
TSC2 |
tuberous sclerosis complex 2 |
WASp |
Wiscott–Aldrich syndrome protein |
ZAP-70 |
ζ-associated protein kinase 70 |