Table 3.
Correlation analyses of serum levels of EL with serum levels of cholesterol in VLDL subclass 1 and ratios indicating lipid content of VLDL particles in MS patients.
| EL (pg/mL) | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Unadjusted | Model 1 | Model 2 | Model 3 | Model 4 | ||||||
| Variable | r | p | r | p | r | p | r | p | r | p |
| VLDL1-C (mg/dL) | −0.26 | 0.040 | −0.16 | 0.211 | −0.19 | 0.142 | −0.21 | 0.095 | −0.24 | 0.055 |
| VLDL-C/VLDL-apoB | −0.38 | 0.002 | −0.32 | 0.013 | −0.32 | 0.011 | −0.33 | 0.008 | −0.37 | 0.003 |
| VLDL-FC/VLDL-apoB | −0.43 | <0.001 | −0.35 | 0.006 | −0.34 | 0.008 | −0.39 | 0.002 | −0.39 | 0.002 |
| VLDL-TG/VLDL-apoB | −0.27 | 0.030 | −0.21 | 0.110 | −0.21 | 0.099 | −0.23 | 0.075 | −0.22 | 0.087 |
| VLDL-PL/VLDL-apoB | −0.31 | 0.012 | −0.25 | 0.051 | −0.23 | 0.077 | −0.28 | 0.025 | −0.28 | 0.029 |
Spearman’s correlation analysis was used to evaluate associations of the serum levels of EL with serum levels of cholesterol in VLDL subclass 1 and the ratios indicating the lipid content of VLDL particles. Model 1: adjusted for age, sex, BMI, and IL-6. Model 2: adjusted for age, sex, BMI, and CRP. Model 3: adjusted for age, sex, and statin. Model 4: adjusted for age, sex, and hypertension. p-values < 0.05 are considered statistically significant and are depicted in bold. ApoB, apolipoprotein B; BMI, body mass index; C, cholesterol; CRP, C-reactive protein; EL, endothelial lipase; HV, healthy volunteer; IL-6, interleukin-6; mL, milliliter; MS, metabolic syndrome patient; N, number; pg, picogram; PL, phospholipid; r, Spearman’s correlation coefficient; TG, triglyceride; VLDL, very low-density lipoprotein.