Table 4.
Correlation analyses of serum levels of EL with ratios indicating lipid content of IDL particles in MS patients.
| EL (pg/mL) | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Unadjusted | Model 1 | Model 2 | Model 3 | Model 4 | ||||||
| Variable | r | p | r | p | r | p | r | p | r | p |
| IDL-C/IDL-apoB | −0.33 | 0.007 | −0.24 | 0.064 | −0.25 | 0.053 | −0.29 | 0.025 | −0.31 | 0.015 |
| IDL-FC/IDL-apoB | −0.31 | 0.011 | −0.22 | 0.093 | −0.23 | 0.068 | −0.28 | 0.026 | −0.30 | 0.018 |
| IDL-TG/IDL-apoB | −0.25 | 0.041 | −0.13 | 0.323 | −0.16 | 0.220 | −0.21 | 0.110 | −0.22 | 0.093 |
| IDL-PL/IDL-apoB | −0.34 | 0.005 | −0.18 | 0.156 | −0.20 | 0.129 | −0.31 | 0.015 | −0.30 | 0.018 |
Spearman’s correlation analysis was used to evaluate associations of the serum levels of EL with the ratios indicating lipid content of IDL particles. Model 1: adjusted for age, sex, BMI, and IL-6. Model 2: adjusted for age, sex, BMI, and CRP. Model 3: adjusted for age, sex, and statin. Model 4: adjusted for age, sex, and hypertension. p-values < 0.05 are considered statistically significant and are depicted in bold. ApoB, apolipoprotein B; BMI, body mass index; C, cholesterol; CRP, C-reactive protein; EL, endothelial lipase; HV, healthy volunteer; IDL, intermediate-density lipoprotein; IL-6, interleukin-6; mL, milliliter; MS, metabolic syndrome patient; N, number; pg, picogram; PL, phospholipid; r, Spearman’s correlation coefficient; TG, triglyceride.