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. 2023 Jun 27;24(13):10710. doi: 10.3390/ijms241310710

Figure 1.

Figure 1

Myocardial hypertrophy. Effect of Empagliflozin administration on myocardial hypertrophy in Ang II-treated rats. (a) Representative images of microscopic transverse sections ((a) left panel) and related microscopic fields ((a) right panel) that show left ventricular hypertrophy with related enlarged cardiomyocyte nuclei. Major and minor nuclear diameters were measured to evaluate the nuclear volume, as described in the Methods. Control (A), control + Empa (B), Ang II (C), Ang II + Empa-treated (D) rats (scale bar 100 µm). (b) Quantification of myocardial hypertrophy in the different groups of rats. Data are means ± SEM. *: p < 0.05. §: p <  0.01.