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. 2023 Jun 28;24(13):10811. doi: 10.3390/ijms241310811

Figure 3.

Figure 3

NIH/3T3 fibroblasts activate HCQ.3 cells even in the absence of COL2 antigen. (A) NIH/3T3 and HCQ.3 cells were co-cultured for 24 h with or without COL2 and glycosylated COL2259–273 peptide, as well as with or without addition of professional APCs. Murine thymic fibroblasts (B), LS48 fibroblasts (C), QB dermal fibroblasts (D), or QB synovial fibroblasts (E), and HCQ.3 cells were co-cultured for 24 h with or without COL2 and glycosylated COL2259–273 peptide, as well as with or without addition of professional APCs. All samples were assessed in triplicates. Data represent ± SEM.