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. 2023 Jun 28;24(13):10773. doi: 10.3390/ijms241310773

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© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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(-) Pseudosemiglabrin-inhibited neuronal apoptosis induced by pilocarpine injection. The result was expressed as mean ± SD. CON: control group; PIL: pilocarpine-induced convulsion group; DIZ: convulsion-induced group pretreated by single oral dose of diazepam 5 mg/kg; SSL: convulsion-induced group pretreated by single oral dose of (-) pseudosemiglabrin 12.5 mg/kg; SSM: convulsion-induced group pretreated by single oral dose of (-) pseudosemiglabrin 25 mg/kg; SSH: convulsion-induced group pretreated by single oral dose of (-) pseudosemiglabrin 50 mg/kg. * p < 0.05, ** p < 0.01 and *** p < 0.001 (vs. PIL group), ++ p < 0.01 and +++ p < 0.001 (vs. SSH group).