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. 2023 Jun 23;24(13):10562. doi: 10.3390/ijms241310562

Table 4.

Association between SEP expression and diverse biological function.

Species Symbol Micro-Peptide Length (aa) Function Category Ref.
Human LINC00948 MLN 46 Inhibits SERCA and regulates Ca2+ transport Micro-peptide related muscle [15]
Human 110017F19Rik
/SMIM6
ELN 56 [146]
Human 1810037I17Rik ALN 65 [146]
Human LOC100507537 DWORF 34 Activates SERCA and regulates Ca2+ transport [131]
Mouse LOC101929726 Minion 84 Promotes myoblast fusion and muscle development [147]
Mouse LOC101929726 Myomixer 84 [16,148]
Fruit Fly Scl SclB <30 Regulates Ca2+ transport [149]
Chicken Six ORF2 SIX1 74 Promotes cell proliferation and is involved in muscle growth [142]
Mouse/
Zerbrefih
MyolncR4/
1500011K16RIK
LEMP 56 Promotes muscle formation and
regeneration in mice
[150]
Human SPAR LINC00961 75 Promotes muscle development [17]
Human miR-155HG miPEP155
(P155)
17 Modulates antigen transport and presentation of antigen presenting cells Micro-peptide related inflammation and
immunity
[21]
Mouse lncRNA 1810058I24Rik Mm47 47 Controls innate immunity [20]
Mouse lncRNA Aw112010 Aw112010 Drives IL-12p40 production and
mediates innate immune
response
[22]
Human IMP _ Regulates inflammatory gene expression [151]
Human
/Mouse
LINC00116/
1500011K16Rik
MOXI
/Mitoregulin
56 Enhances mitochondrial β-oxidation Micro-peptide related metabolism [19]
Mouse LINC00116 Mtln 56 Supports mitochondrial super-complexes and respiratory efficiency [18]
Human LINC-PINT PINT87aa 87 Tumor suppressor in glioblastoma Micro-peptides related tumors [152]
Human LINC00278 YY1BM 21 Promotes apoptosis and downregulates the survival rate of
ESCC cells
[153]
Human circFNDC3B cirFND3B-218aa 218 Inhibits the expression of
oncogene Snail and promotes CRC
[154]
Human circPPP1R12A PPP1R12A-C 73 Activates Hippo-YAP signaling
pathway and inhibits CRC
[155]
Human Meloe MELOE-1 46 Involved in T cell immune surveillance; optimal T cell target
for melanoma immunotherapy
[156]
Human MELOE-2 39 [157]
Human LINC00665 CIP2A-BP 52 Inhibits tumor invasion and metastasis [158]
Human LINC00998 SMIM30 59 Promotes cell proliferation and migration [139]
Human NCBP2-AS2 KRASIM 99 Inhibits carcinogenic signaling in hepatocellular carcinoma
cells
[159]
Human UBAP1-AST6 BAP1-AST6 (aa) - Promotes cell proliferation [160]
Human HOXB-AS3 HOXB-AS3 53 Inhibits cell proliferation, invasion, and metastasis [161]
Human CTD-2256P15.2 PACMP 44 Regulates cancer progression and drug resistance by modulating DNA damage response [26]
Human Rps41 RPS4XL _ Inhibition of hypoxia-induced
proliferation of pulmonary artery smooth muscle cells
Other diseases [162]