ND |
Neurodegenerative disease |
AD |
Alzheimer’s disease |
APP |
Amyloid precursor protein |
Aβ |
Amyloid beta peptide |
HCHWA-D |
Hereditary cerebral hemorrhage with amyloidosis |
PiD |
Pick’s disease |
GFAP |
Glial fibrillary acidic protein |
SPECT |
Single-photon emission computed tomography |
PET |
Positron emission tomography |
APOE |
Apolipoprotein E |
BBB |
Brain Blood Barrier |
HDL |
High density lipoprotein |
CNS |
Central Nervous System |
NFTs |
Neurofibrillary Tangles |
GWAS |
Genome-wide association study |
PP2A |
Protein phosphatase 2A |
FTD |
Frontotemporal Dementia |
CTD |
Chronic traumatic encephalopathy |
CBD |
Corticobasal degeneration |
DAM |
Disease-associated microglia |
MGnD |
Microglial neurodegenerative |
TREM2 |
Triggering receptor expressed on myeloid cells 2 |
CRP |
C-reactive protein |
MCI |
Mild cognitive impairment |
MAPT |
Microtubule-associated protein tau |
PSP |
Progressive supranuclear palsy |
PHF |
Abnormally hyperphosphorylated taus |
CL |
Centiloids |
SUVR |
Standardized Uptake Ration |
PD |
Parkinson’s disease |
SNpc |
Substantia nigra pars compacta |
DA |
Dopamine |
DMV |
Dorsal motor nucleus of vagus |
OB |
Olfactory bulb |
LC |
Locus coeruleus |
IML |
Intermediolateral nucleus in spinal cord |
ENS |
Enteric nervous system |
EOPD |
Early-onset Parkinson’s disease |
mitoQC |
Mitochondrial quality control |
DFO |
Deferrioxamine |
DFP |
Deferiprone |
HD |
Huntington’s disease |
MSNs |
Medium spiny neurons |
mHTT |
Mutation of the huntingtin gene |
HTT |
Huntingtin gene |
CBP |
cAMP response element-binding protein |
MSK1 |
Mitogen-activated and stress-activated protein kinase 1 |
PGC-1a |
Proliferator-activated receptor gamma coactivator alpha |
HDAC |
Histone deacetylase |
BDNF |
Brain-derived neurotrophic factor |
ASOs |
Antisense oligonucleotides |
RNAi |
RNA interference |
CoQ10 |
Coenzyme Q10 |
CREST-E |
Creatine safety tolerability efficacy in Huntington’s disease |
ALS |
Amyotrophic lateral sclerosis |
FALS |
Familial amyotrophic lateral sclerosis |
DPR |
Dipeptide repeat proteins |
FUS |
Fused in Sarcoma |
miRNA |
Micro RNA |
PTM |
Post-translational modification |
UMN |
Upper motor neuron |
LMN |
Lower motor neuron |
PMA |
Progressive muscular atrophy |
PBP |
Pseudobulbar Palsy |