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. 2023 Jul 6;24(13):11135. doi: 10.3390/ijms241311135
ROS Reactive Oxygen Species
SIRT1 Sirtuin 1
SRT2104 SIRT1 activator
CON Control
HU Hindlimb Unloading
Nox2 NADPH oxidase-2
H2O2 hydrogen peroxide
PGC-1α peroxisome proliferator-activated receptor γ coactivator-1α
CS Citrate synthase
CCO cytochrome c oxidase
FCR flux control ratio
PCI oxidative phosphorylation supported by complex I
PCI+II maximal coupled oxidative phosphorylation
ECI+II maximal noncoupled electron transfer
ECII electron transfer supported by complex II only
SOD Superoxide dismutase
GPx glutathione peroxidase
ATP adenosine triphosphate
MIM mitochondrial isolation medium