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. 2023 Jun 30;24(13):10959. doi: 10.3390/ijms241310959

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© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Caspase 3/7 activity in BxPC-3 (A) and PC-3 (B) cells following 24-h incubation with MM-compounds used at 0.5xIC₅₀, IC₅₀, and 2xIC₅₀ concentrations and 2 µM SN-38 (used as positive control). Caspase 8 (C) and caspase 9 (D) activity in BxPC-3 cells treated with the same concentrations of the compounds and for the same incubation time. The data are presented as relative fluorescence units (RFU) ± SD. The differences between the experimental samples and control samples were estimated using an ANOVA followed by Tukey’s post-hoc test (p < 0.05). * Significant difference compared with negative control; # Significant difference compared with positive control (2 µM SN-38).