ABL	tyrosine-protein kinase ABL
ADMET	absorption, distribution, metabolism, excretion, and toxicity
AIFM1	apoptosis-inducing factor, mitochondrion-associated, 1
AKT	serine/threonine-protein kinase AKT
AO/EB	acridine orange/ethidium bromide
APAF-1	apoptotic protease-activating factor 1
BAD	BCL2-associated agonist of cell death
BAG1	BCL2-associated athanogene
BCL10	B-cell CLL/lymphoma 10
BCL2L10	BCL2-like 10 (apoptosis facilitator)
BE	binding energy
BIRC5	baculoviral IAP repeat containing 5
BNIP3	BCL2/adenovirus E1B 19 kDa interacting protein 3
BNIP3L	BCL2/adenovirus E1B 19 kDa interacting protein 3-like
BrdU	Bromodeoxyuridine
BSA	bovine serum albumin
BTK	Bruton’s tyrosine kinase
CAs	carbonic anhydrases
CASP1	caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)
CASP14	caspase 14, apoptosis-related cysteine peptidase
CASP2	caspase 2, apoptosis-related cysteine peptidase
CASP6	caspase 6, apoptosis-related cysteine peptidase
CARD	caspase recruitment domain
CDKs	cyclin-dependent kinases
CD27	CD27 molecule
CD70	CD70 molecule
CHK1	serine/threonine-protein kinase CHK1
CIDEA/B	Cell death-inducing DFFA-like effector A/B
CLL	chronic lymphocytic leukemia
CRADD	CASP2 and RIPK1 domain containing adaptor with death domain
CYP	cytochrome
DCF	2′,7′-dichlorofluorescein
DCFH2	2′,7′-dichlorodihydrofluorescein
DCFH-DA	2,7-dichlorodihydrofluorescein diacetate
DFFA	DNA fragmentation factor, 45 kDa, alpha polypeptide
DISC	death-inducing signaling complex
DPT	developmental toxicity potential
EMM	molecular mechanic’s energies
ESP	electrostatic potential
FADD	FAS-associated death domain protein
FAS	Fas (TNF receptor superfamily, member 6)
FBS	fetal bovine serum
GADD45α	growth arrest and DNA-damage-inducible, alpha
GB/SA	generalized Born/Surface continuum solvent model
GNP	non-polar solvation
HCl	hydrochloric acid
HLG	HOMO-LUMO energy gap
HOMO	highest occupied molecular orbital
LD50	50% lethal dose
LOAEL	lowest observable adverse effects level
LUMO	lowest occupied molecular orbital
MCL	mantle cell lymphoma
MD	molecular dynamics
MESP	molecular electrostatic potential
MLKL	mixed lineage kinase domain like pseudokinase
MMP	mitochondrial membrane potential
mTOR	mammalian target of rapamycin kinase
NAIP	NLR family, apoptosis inhibitory protein
NF-κB	nuclear factor kappa-B
NOD1	nucleotide-binding oligomerization domain containing 1
OPLS-AA	optimized potential liquid solvation-all atom
OPS	optimal prediction space
PBS	phosphate-buffered saline
P21	Cyclin-dependent kinase inhibitor 1 (also known as Waf1/Cip1)
PD-1	programmed cell death protein 1
PD-L1	programmed death-ligand 1
PHA	Paraformaldehyde
PI	propidium iodide
PPB	plasma protein binding
PS	phosphatidylserine
PYCARD	PYD and CARD domain containing
QSAR	quantitative structure-activity relationship
RFU	relative fluorescence units
RIPK2	receptor-interacting serine-threonine kinase 2
RMSD	trajectory root mean square deviation
RMSF	root mean square fluctuation
ROS	reactive oxygen species
SASA	solvent accessible surface area
sICAM-1	soluble intercellular adhesion molecule-1
SMILES	simplified molecular input line entry system
TOPKAT	toxicity prediction by computer-aided technology
TNF	tumor necrosis factor
TNFRSF10B	tumor necrosis factor receptor superfamily, member 10b
TNFRSF11B	tumor necrosis factor receptor superfamily, member 11b
TNFRSF1A	tumor necrosis factor receptor superfamily, member 1A
TNFSF10	tumor necrosis factor (ligand) superfamily, member 10
TP53	cellular tumor antigen p53
TRADD	tumor necrosis factor receptor type 1-associated DEATH domain
TRAF2	TNF receptor-associated factor 2
TRAIL	tumor necrosis factor-related apoptosis inducing ligand
λem	emission wavelength
λex	excitation wavelength