Table 7.
Associations of rs429358 and rs7412 genotypes with MI.
| Sex | Genotype | Study Sample | Myocardial Infarction |
OR (95% CI) | p | ||
|---|---|---|---|---|---|---|---|
| n | % | n | % | ||||
| Males | ɛ2/ɛ4 | 18 | 2.1 | 10 | 7.8 | 3.931 (1.772–8.720) | <0.0001 * |
| ɛ2/ɛ2 | 6 | 0.7 | 1 | 0.8 | 1.112 (0.133–9.309) | 0.922 | |
| ɛ2/ɛ3 | 128 | 15.0 | 18 | 14.0 | 0.927 (0.544–1.579) | 0.780 | |
| ɛ3/ɛ3 | 525 | 61.5 | 81 | 63.3 | 1.077 (0.733–1.582) | 0.707 | |
| ɛ3/ɛ4 | 161 | 18.9 | 17 | 13.3 | 0.658 (0.384–1.128) | 0.126 | |
| ɛ4/ɛ4 | 15 | 1.8 | 1 | 0.8 | 0.440 (0.058–3.359) | 0.416 | |
| Females | ɛ2/ɛ4 | 24 | 1.9 | 3 | 5.5 | 2.947 (0.860–10.102) | 0.071 |
| ɛ2/ɛ2 | 11 | 0.9 | - | - | - | - | |
| ɛ2/ɛ3 | 155 | 12.4 | 6 | 10.9 | 0.865 (0.365–2.053) | 0.742 | |
| ɛ3/ɛ3 | 778 | 62.2 | 32 | 58.2 | 0.844 (0.448–1.460) | 0.544 | |
| ɛ3/ɛ4 | 256 | 20.5 | 13 | 23.6 | 1.202 (0.635–2.273) | 0.571 | |
| ɛ4/ɛ4 | 26 | 2.1 | 1 | 1.8 | 0.872 (0.116–6.544) | 0.894 | |
| Total | ɛ2/ɛ4 | 42 | 2.0 | 13 | 7.1 | 3.753 (1.976–7.127) | <0.0001 * |
| ɛ2/ɛ2 | 17 | 0.8 | 1 | 0.6 | 0.674 (0.089–5.095) | 0.701 | |
| ɛ2/ɛ3 | 283 | 13.5 | 24 | 13.1 | 0.971 (0.621–1.518) | 0.896 | |
| ɛ3/ɛ3 | 1303 | 62.0 | 113 | 61.7 | 0.991 (0.726–1.352) | 0.955 | |
| ɛ3/ɛ4 | 417 | 19.8 | 30 | 16.4 | 0.793 (0.528–1.190) | 0.261 | |
| ɛ4/ɛ4 | 41 | 1.9 | 2 | 1.1 | 0.556 (0.133–2.316) | 0.413 | |
* Statistical significance.