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. 2023 Jul 2;12(13):4446. doi: 10.3390/jcm12134446

Figure 1.

Figure 1

The association between the overall effects of circRNA expression on the process of atherosclerosis. Up-regulation of circRNAs in atherosclerosis was found to be most associated with harmful (78%) effects, while downregulation was most associated with protective mechanisms (70%). Equivocal effects were demonstrated in 10% and 26% of studies in which circRNAs were observed to be up-regulated and downregulated, respectively.