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. 2023 Jul 6;24(13):11156. doi: 10.3390/ijms241311156

Table 2.

Effects of exercise on chemokines secretion in humans.

Cytokine Physical Activity Training Level of the Subjects Response References
IL-8 Marathon 42 km Trained runners Increased level of IL-8 6.7-fold 30 min after running [72]
Ultramarathon 160 km Trained runners Increased level of IL-8 2.5-fold after running [28]
1 h cycling Trained cyclists Significantly increased level of IL-8 after cycling [73]
1 h cycling Trained cyclists 30-fold increased IL-8 mRNA in skeletal muscles immediately after exercise [73]
MCP-1 1 h rowing ergometer test Trained rowers Significantly increased level of MCP-1 after test [42]
Marathon 42 km Trained runners Significantly increased level of MCP-1 after running [74]
Wingate Anerobic Test Trained soccer players Minimal MCP-1 mRNA expression after the test and continuous increase over time with a maximum at the sixth hour after test [75]
Wingate Anerobic Test Untrained individuals Significantly increased MCP-1 mRNA expression immediately after the test and then decreased to a lower level [75]
Treadmill test Trained runners Significantly increased level of MCP-1 after running [66]
MIP-1α Marathon 42 km Trained runners Increased level of MIP-1α 3.5-fold 30 min after running [72]
MIP-1β Marathon 42 km Trained runners Increased level of MIP-1β 4.1-fold 30 min after running [72]