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. 2023 Jun 28;12(13):4354. doi: 10.3390/jcm12134354

Table 2.

The characteristics of patients who developed late-onset cholecystitis.

Parameters Univariable Analysis Multivariate Analysis
Late-Onset Cholecystitis No Late-Onset Cholecystitis p-Value Odds Ratio 95% Cl p-Value
No. of patients 25 (24.0) 79 (76.0)
Gender (M/F) 10 (40)/15 (60) 45 (57.0)/34 (43.0) 0.139
Age (year, mean ± SD) 71.4 ± 8.5 72.3 ± 11.5 0.690
Presence of GB stone 5 (20) 9 (11.4) 0.272 3.295 0.791–13.722 0.101
Presence of diabetes 5 (20.0) 21 (26.6) 0.508 0.707 0.203–2.458 0.586
AST 75.0 ± 60.1 95.8 ± 130.3 0.395
ALT 98.0 ± 82.2 84.3 ± 79.5 0.533
TB 6.4 ± 4.9 10.1 ± 8.9 0.418
DB 4.0 ± 3.2 6.1 ± 5.5 0.418
Pre-ERCP cholangitis 8 (32.0) 18 (22.8) 0.354 1.295 0.434–3.865 0.643
GB filling with contrast medium 11 (44) 26 (32.9) 0.313 1.135 0.395–3.261 0.814
Invasion of the cystic duct orifice 20 (80) 52 (65.8) 0.219 2.345 0.736–7.474 0.150
GB filling with contrast medium and invasion of the cystic duct 9 (36) 14 (17.7) 0.055
Length of the common part of the Y-stent 7.3 ± 0.9 7.1 ± 1.1 0.364 1.332 0.786–2.257 0.287
Previous early-onset cholecystitis 2 (8.0) 5 (6.3) 0.771
Stent patent days 256.4 ± 177.1 115.0 ± 126.1 0.268
Stent obstruction 21 (84.0) 41 (51.9) 0.004 5.879 1.641–21.059 0.007
- Obstruction reason;
  ingrowth/overgrowth/
  sludge/stone
7 (33.3)/10 (47.6)
/3 (14.2)/1 (4.8)
15 (36.6)/19 (46.3)
/6 (14.6)/1 (2.4)
0.967
Repeated procedure due to stent obstruction 21 (84.0) 35 (44.3) 0.001
- PTBD/
  plastic stent/c ERCP/
  metal stent/c ERCP
12 (57.1)/7 (33.3)/2 (9.5) 20 (57.1)/12 (34.3)/3 (8.6) 0.992
Survival days 385.0 ± 245.1 151.7 ± 156.5 0.239

Data are presented as mean ± SD. ERCP, endoscopic retrograde cholangiopancreatography; GB, gallbladder; AST, aspartate transaminase; ALT, alanine transaminase; TB, total bilirubin; DB, direct bilirubin.