Table 3.
Comparison of patients with IBD at the time of the diagnosis of PI.
| PI at the Time of IBD Diagnosis (n = 48, 27.3%) |
PI after IBD Diagnosis (n = 128, 72.7%) |
p | |
|---|---|---|---|
| Age (median, range) | 14.0 (2–17) | 13.5 (1–17) | 0.73 |
|
Gender (n, %) Males |
26 (54.2) | 68 (53.1) | 0.96 |
| CD (n, %) | 15 (31.3) | 61 (47.7) | 0.07 |
| UC (n, %) | 33 (68.8) | 67 (52.3) | 0.07 |
| IBD activity (n, %) | |||
| Remission | 0 (0.0) | 29 (22.7) | NA |
| Mild | 11 (22.9) | 40 (31.3) | 0.37 |
| Moderate | 23 (47.9) | 38 (29.7) | 0.04 |
| Severe | 14 (29.2) | 21 (16.4) | 0.09 |
| PUCAI (median, range) | 45.0 (10–85) | 30.0 (0–75) | 0.03 |
| PCDAI (median, range) | 38.5 (0–65) | 25.0 (0–75) | 0.002 |
| Colon involvement (n, %) | 44 (91.7) | 126 (98.4) | 0.08 |
| Amylase, IU/L (median, range) | 148 (34–1990) | 109 (33–501) | 0.008 |
| Lipase, IU/L (median, range) | 450 (60–11,180) | 430 (35–5689) | 0.66 |
| PI (n, %): | |||
| AP | 14 (29.2) | 63 (49.2) | 0.026 |
| Severity of AP: | |||
| Mild | 12 (85.7) | 60 (95.2) | 0.47 |
| Moderately severe | 2 (14.3) | 3 (4.8) | NA |
| Severe | 0 (0.0) | 0 (0.0) | NA |
| HA/HL | 26 (54.2) | 62 (48.4) | 0.61 |
| AIP | 6 (12.5) | 3 (2.3) | NA |
| CP | 2 (4.2) | 0 (0.0) | NA |
IBD—inflammatory bowel disease, CD—Crohn’s disease, UC—ulcerative colitis, PUCAI—Pediatric Ulcerative Colitis Activity Index, PCDAI—Pediatric Crohn’s Disease Activity Index, PI—pancreatic involvement, AP—acute pancreatitis, HA/HL—hyperamylasemia/hyperlipasemia, AIP—autoimmune pancreatitis, CP—chronic pancreatitis, and NA—not applicable.